Mechanical properties of femoral trabecular bone in dogs

authored by: Thomas Pressel, Anas Bouguecha, Ute Vogt, Andrea Meyer-Lindenberg, Bernd-Arno Behrens, Ingo Nolte, Henning Windhagen
Abstract: Background: Studying mechanical properties of canine trabecular bone is important for a better understanding of fracture mechanics or bone disorders and is also needed for numerical simulation of canine femora. No detailed data about elastic moduli and degrees of anisotropy of canine femoral trabecular bone has been published so far, hence the purpose of this study was to measure the elastic modulus of trabecular bone in canine femoral heads by ultrasound testing and to assess whether assuming isotropy of the cancellous bone in femoral heads in dogs is a valid simplification. Methods: From 8 euthanized dogs, both femora were obtained and cubic specimens were cut from the centre of the femoral head which were oriented along the main pressure and tension trajectories. The specimens were tested using a 100 MHz ultrasound transducer in all three orthogonal directions. The directional elastic moduli of trabecular bone tissue and degrees of anisotropy were calculated. Results: The elastic modulus along principal bone trajectories was found to be 11.2 GPa ± 0.4, 10.5 ± 2.1 GPa and 10.5 ± 1.8 GPa, respectively. The mean density of the specimens was 1.40 ± 0.09 g/cm³. The degrees of anisotropy revealed a significant inverse relationship with specimen densities. No significant differences were found between the elastic moduli in x, y and z directions, suggesting an effective isotropy of trabecular bone tissue in canine femoral heads. Discussion: This study presents detailed data about elastic moduli of trabecular bone tissue obtained from canine femoral heads. Limitations of the study are the relatively small number of animals investigated and the measurement of whole specimen densities instead of trabecular bone densities which might lead to an underestimation of Young's moduli. Publications on elastic moduli of trabecular bone tissue present results that are similar to our data. Conclusion: This study provides data about directional elastic moduli and degrees of anisotropy of canine femoral head trabecular bone and might be useful for biomechanical modeling of proximal canine femora.
Organisation(s): Institute of Metal Forming and Metal Forming Machines
External Organisation(s): Hannover Medical School (MHH)
University of Veterinary Medicine of Hannover, Foundation
Type: Article
Journal: BioMedical Engineering Online
Volume: 4
No. of pages: 6
ISSN: 1475-925X
Publication date: 17.03.2005
Publication status: Published
Peer reviewed: Yes
ASJC Scopus subject areas: Radiological and Ultrasound Technology, Biomaterials, Biomedical Engineering, Radiology Nuclear Medicine and imaging
Electronic version(s): https://doi.org/10.1186/1475-925X-4-17 (Access: Open)
https://doi.org/10.1186/1475-925X-4-66 (Access: Open)
: Details in the research portal "Research@Leibniz University"

BibTeX

@article{7a5b7870df61447c8514e15d994790d8,
title = "Mechanical properties of femoral trabecular bone in dogs",
abstract = "Background: Studying mechanical properties of canine trabecular bone is important for a better understanding of fracture mechanics or bone disorders and is also needed for numerical simulation of canine femora. No detailed data about elastic moduli and degrees of anisotropy of canine femoral trabecular bone has been published so far, hence the purpose of this study was to measure the elastic modulus of trabecular bone in canine femoral heads by ultrasound testing and to assess whether assuming isotropy of the cancellous bone in femoral heads in dogs is a valid simplification. Methods: From 8 euthanized dogs, both femora were obtained and cubic specimens were cut from the centre of the femoral head which were oriented along the main pressure and tension trajectories. The specimens were tested using a 100 MHz ultrasound transducer in all three orthogonal directions. The directional elastic moduli of trabecular bone tissue and degrees of anisotropy were calculated. Results: The elastic modulus along principal bone trajectories was found to be 11.2 GPa ± 0.4, 10.5 ± 2.1 GPa and 10.5 ± 1.8 GPa, respectively. The mean density of the specimens was 1.40 ± 0.09 g/cm3. The degrees of anisotropy revealed a significant inverse relationship with specimen densities. No significant differences were found between the elastic moduli in x, y and z directions, suggesting an effective isotropy of trabecular bone tissue in canine femoral heads. Discussion: This study presents detailed data about elastic moduli of trabecular bone tissue obtained from canine femoral heads. Limitations of the study are the relatively small number of animals investigated and the measurement of whole specimen densities instead of trabecular bone densities which might lead to an underestimation of Young's moduli. Publications on elastic moduli of trabecular bone tissue present results that are similar to our data. Conclusion: This study provides data about directional elastic moduli and degrees of anisotropy of canine femoral head trabecular bone and might be useful for biomechanical modeling of proximal canine femora.",
author = "Thomas Pressel and Anas Bouguecha and Ute Vogt and Andrea Meyer-Lindenberg and Bernd-Arno Behrens and Ingo Nolte and Henning Windhagen",
year = "2005",
month = mar,
day = "17",
doi = "10.1186/1475-925X-4-17",
language = "English",
volume = "4",
journal = "BioMedical Engineering Online",
issn = "1475-925X",
publisher = "BioMed Central Ltd.",
number = "17",
}